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TUMOR NECROSIS FACTORS
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DeCS
Descriptor
English
:
Tumor Necrosis Factors
Descriptor
Spanish
:
Factores de Necrosis Tumoral
Descriptor
Portuguese
:
Fatores de Necrose Tumoral
Tree Number:
D12.644.276.374.750
D12.644.276.972
D12.776.467.374.750
D12.776.467.972
D23.529.374.750
D23.529.972
Definition
English
:
A
family
of
proteins
that were originally identified by their ability to cause
NECROSIS
of
NEOPLASMS
. Their necrotic effect on
cells
is mediated through TUMOR
NECROSIS
FACTOR RECEPTORS which induce
APOPTOSIS.
History Note
English
:
2005
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
38737
Unique Identifier:
D048069
Occurrence in VHL
:
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